Research has shown that the utilization of human cell and tissue products from the umbilical cord and alternative birth tissues may have a massive affect on the major injuries and human physical ailments.
We have seen a six fold increase in engraftment due to the combination of the various compartments.
Bone marrow-derived mesenchymal stem cells (MSCs) have been found to promote engraftment after hematopoietic stem cell transplantation. However, harvesting MSCs from bone marrow involves an invasive procedure.
Then again, MSCs can be easily obtained from umbilical cords without harm to the donors. Cord tissue mesenchymal stem cells have a shorter doubling time than adult mesenchymal stem cells and also have more potential divisions.
They also secrete and contain a more potent and regenerative profile of growth factors. The fitness of adult mesenchymal stem cells, as well as the growth factors they secrete, declines with age. Medical research has shown that birth tissue has greater fitness than msc derived allograft will have greater fitness than adult mesenchymal stem cells due to the higher concentration of growth factors and the younger and more fit cells. Due to the screening process and probability, the allograft is less likely to contain any genetic or epigenetic defects present in the patient’s tissues.